SiM20 Posters

13 Sensors in Medicine 2020 Acknowledgement The authors acknowledge partial financial support by the Sensor Innovation Initiative of King Abdullah University of Science and Technology, Thuwal, Saudi-Arabia. Conclusion The here presented planar LIG electrode structure on flexible polyimide substrate with a straight- forward production procedure is perfectly suited for the development of an affordable wearable setup for a non-invasive determination of physiological relevant concentrations of various biomarkers in sweat. Results Bauer M, Wunderlich L, Weinzierl F, Lei Y, Duerkop A, Alshareef HN, Baeumner AJ. Electrochemical Multi-Analyte Point-of-Care Perspiration Sensors Using On Chip Three-Dimensional Graphene Electrodes . ABC; 2020. [in press] The three sensing strategies were successfully combined to a multianalyte sensor system. The platform enables the determination of the analytes within their physiological relevant ranges. It shows a good performance at different pH values, with sweat collecting tissues, on a model skin system and furthermore in synthetic sweat as well as in artificial tear fluid. One analytical cycle totals 75 seconds, and hence allows a quasi-continuous and simultaneous monitoring of all analytes with an economical electrode material. A potentiometric two-electrode setup with a potassium ion-selective electrode in combination with an electrodeposited silver/silver chloride reference electrode was investigated. The over-all electrolyte concentration was quantified by electrochemical impedance spectroscopy at fixed frequency, using a kidney-shaped interdigitated LIG electrode structure. A chronoamperometric sensor for the detection of D-glucose and L-lactate with a three-electrode setup was developed. LIG with chemical deposited Prussian blue as electron transfer mediator served as working electrode. A biocompatible chitosan membrane on top provided a suitable environment for the enzymes lactate oxidase and glucose oxidase.