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5

Sensor100

February 2016

Company Profile:

Profusa Inc.

Profusa Unveils First Biointegrated Sensors for Long-term

Continuous Monitoring of Body Chemistry

At the Consumer Elec-

tronics Show in January,

South San Francisco based

Profusa showed off an

upcoming injectable sensor

that can be used to con-

tinuously monitor oxygen

levels in tissue. Measuring

only 3-5 millimeters long

and a tiny 500 microns in

diameter, the biosensor

can be injected into tissue

with just a hypodermic needle. It consists of a soft hydrogel scaffold that

allows it to be biologically compatible with the surrounding tissue with-

out any foreign body response.The sensor also contains a special chemical

marker that changes fluorescence depending on the amount of oxygen that

reacts with it. An optical reader placed on the skin measures the fluores-

cence and relays the data to a smartphone.The biosensor can last as long

as two years (at which point the chemical marker begins to lose its poten-

cy), and because it contains no electronics and is completely biocompatible

there’s no need to remove it.

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